Capture Hi-C

Capture Hi-C for focused 3D genome interaction mapping at specific loci

When you need focused 3D-genome interaction maps at specific loci, Capture Hi-C combines proximity ligation with target-region enrichment for fine-scale resolution of promoter-enhancer interactions, structural variant breakpoints, and topological domain boundaries.

Pick by panel and sample.

1. Capture panel. Whole-promoter capture panels for human and mouse are commercial. Custom panels for specific loci require design and ordering.
2. Sample type. Cell line versus primary tissue versus FFPE. Sample quality affects Hi-C library success.
3. Analytical pipeline. Specialised analysis required. Vendor pipeline versus open-source.
4. Pilot studies. Use a commercial promoter-capture panel before investing in custom design. Commercial panels have validated workflows.

Arima supplies Capture Hi-C in this inventory.