ATAC & ISAC Sequencing

ATAC-seq and ISAC reagents for genome-wide chromatin accessibility mapping from low cell input

When you need genome-wide chromatin accessibility maps from low cell input, ATAC-seq uses Tn5 tagmentation directly on intact nuclei. ISAC and related variants extend the method. Works from a few thousand cells; single-cell variants exist.

Pick by input and variant.

1. Bulk ATAC-seq. From 5,000 cells; population accessibility profiles.
2. Single-cell ATAC. Thousands of cells in parallel for heterogeneity.
3. CUT&Tag. For protein-specific profiling, alternative workflow.
4. Platform compatibility. Illumina-standard library prep.
5. Sequencing depth. Match depth to question; bulk needs lower depth, single-cell needs more.

EpigenTek leads ATAC library prep reagents.