shRNA Target Gene Sets

Select the shRNA Target Gene Set to knockdown your gene of interest

HuSH-29 Hairpin Expression Constructs

The well-known HuSH-29 Hairpin Expression Constructs are characterized by improved efficacy and lowest interferon response. OriGene uses a proven 29-mer short hairpin design, which has been demonstrated to be more effective than conventional 21-mer versions. Steps have been taken to continually improve and optimize the algorithm used in sequence selection for HuSH-29 shRNA products. 

• Genome-wide coverage for human, mouse and rat 
• Multiple vector selection: Lentiviral, Retroviral or AAV
• Multiple reporter selection: tGFP, tRFP, no reporter
• Guaranteed knockdown of ≥70%*
• Set of 4 gene-specific shRNAs and a scrambled negative control
• Custom shRNA service is also available

*For all HuSH shRNA products, OriGene provides a performance guarantee. If a set of OriGene constructs fails to produce at least 70% gene expression knockdown, our scientists will work with you to pinpoint the problem and, if necessary, OriGene will replace your HuSH constructs with another set against that target gene, free of charge.