logo

SKU: E-AB-65947-120ul-ELS

WWOX Polyclonal Antibody

Specifications

Specification Details
Species Reactivity Human,Mouse
Application IF
Label Unconjugated
Synonyms D16S432E,EIEE28,FOR,FRA16D,HHCMA56,PRO0128,SCAR12,SDR41C1,WOX1,WWOX
Gene ID 51741
UniProt ID Q9NZC7
Immunogen Recombinant fusion protein of human WWOX (NP_057457.1).
Background This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.
Primary / Secondary Primary Antibody
Isotype IgG
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality Polyclonal
Host Rabbit

Resources

PDF

Datasheet

Catalog Number
E-AB-65947-120ul-ELS
Name
WWOX Polyclonal Antibody
Price(120 ul)
Pack Size
← Back to products