SKU: A66030-100-EP
UBR2 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | ELISA, WB |
| Label | Unconjugated |
| Synonyms | E3 ubiquitin-protein ligase UBR2, N-recognin-2, Ubiquitin-protein ligase E3-alpha-2, Ubiquitin-protein ligase E3-alpha-II, UBR2, C6orf133, KIAA0349 |
| UniProt ID | Q8IWV8 |
| Immunogen | Recombinant Human E3 ubiquitin-protein ligase UBR2 protein (101-439AA) |
| Background | E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A66030-100-EP
Name
UBR2 Polyclonal Antibody
Price(100 ul)
Pack Size