SKU: A66009-050-EP
Txnip Polyclonal Antibody, Biotin Conjugated
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | ELISA |
| Label | Biotin |
| Synonyms | Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1, Txnip, Vdup1 |
| UniProt ID | Q8BG60 |
| Immunogen | Recombinant Mouse Thioredoxin-interacting protein (1-397AA) |
| Background | May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A66009-050-EP
Name
Txnip Polyclonal Antibody, Biotin Conjugated
Price(5000 ul)
Pack Size