SKU: E-AB-52657-20ul-ELS
TUBGCP4 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | WB |
| Label | Unconjugated |
| Synonyms | 76P, FLJ14797, Gamma tubulin complex component 4, Gamma tubulin ring complex protein (76p gene), Gamma tubulin ring complex protein, Gamma-ring complex protein 76 kDa, GCP 4, GCP4, Grip76, h76p, hGCP4, Hgrip76, TUBGCP 4, TUBGCP4, Tubulin gamma complex associated protein 4 |
| Accession No. | BC009870 |
| UniProt ID | Q9UGJ1 |
| Immunogen | Fusion protein of human TUBGCP4 |
| Background | This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.TUBGCP4 (Tubulin Gamma Complex Associated Protein 4) is a Protein Coding gene. Diseases associated with TUBGCP4 include Microcephaly And Chorioretinopathy, Autosomal Recessive, 3 and Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include structural constituent of cytoskeleton. An important paralog of this gene is TUBGCP6. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 0.66 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-52657-20ul-ELS
Name
TUBGCP4 Polyclonal Antibody
Price(20 ul)
Pack Size