SKU: T6587-GVO-ABM
TLR3 -/-MDA5 -/- CRISPR Knockout DF-1 Stable Cell Line
Chicken (Galline)
Dry Ice
Specifications
| Specification | Details |
|---|---|
| Organism | Chicken (Galline) |
| Tissue Origin | Embryo |
| Additional Information | The TLR3 -/- MDA5 -/- CRISPR Knockout DF-1 Cell Line is a dual gene knockout model derived from the DF-1 chicken embryonic fibroblast cell line, engineered using CRISPR/Cas9 to stably disrupt both TLR3 (Toll-Like Receptor 3) and MDA5 (Melanoma Differentiation-Associated Protein 5) genes. This cell line serves as a unique and powerful tool for dissecting the innate immune response to viral RNA, specifically targeting two major sensing pathways: endosomal RNA detection via TLR3 and cytoplasmic long dsRNA recognition via MDA5. |
Catalog Number
T6587-GVO-ABM
Name
TLR3 -/-MDA5 -/- CRISPR Knockout DF-1 Stable Cell Line
Price(1 x 10^6 cells)
Pack Size
1 x 10^6 cells