SKU: A78657-100-EP
STAT5B Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IHC-P, IF/ICC, IP, ELISA |
| Label | Unconjugated |
| Synonyms | STAT5; GHISID2; 5B |
| Accession No. | P51692 |
| UniProt ID | P51692 |
| Immunogen | Recombinant protein (or fragment). Please contact BioCat for more information. |
| Background | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | Lot specific. Please inquire or refer to the datasheet included in the product pouch. |
| Buffer | Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3. |
| Additional Information | Conjugation service and the corresponding secondary antibody are available. |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A78657-100-EP
Name
STAT5B Polyclonal Antibody
Price(100 ul)
Pack Size
100 ul