logo

SKU: E-AB-16244-120ul-ELS

STAT2 Polyclonal Antibody

Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application WB, IHC
Label Unconjugated
Synonyms Homo sapiens interferon alpha induced transcriptional activator, interferon alpha induced transcriptional activator, ISGF 3, ISGF3, MGC59816, P113, signal transducer and activator of transcription 2 113kD, Signal transducer and activator of transcription 2, STAT113, Stat2, STAT2
Gene ID 6773
Accession No. NP_005410
UniProt ID P52630
Immunogen Synthetic peptide of human STAT2
Background The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
Primary / Secondary Primary Antibody
Isotype IgG
Concentration 0.5 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Clonality Polyclonal
Host Rabbit

Resources

PDF

Datasheet

Catalog Number
E-AB-16244-120ul-ELS
Name
STAT2 Polyclonal Antibody
Price(120 ul)
Pack Size
← Back to products