SKU: A65874-100-EP
SMG6 Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA, IHC, IF |
| Label | Unconjugated |
| Synonyms | Telomerase-binding protein EST1A, EST1-like protein A, Ever shorter telomeres 1A, Smg-6 homolog, Telomerase subunit EST1A, hSmg5/7a, SMG6, C17orf31, EST1A, KIAA0732 |
| UniProt ID | Q86US8 |
| Immunogen | Recombinant Human Telomerase-binding protein EST1A protein (251-511AA) |
| Background | Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER). |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A65874-100-EP
Name
SMG6 Polyclonal Antibody
Price(10000 ul)
Pack Size