SKU: A76658-100-EP
SF3B1 Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IF/ICC, ELISA |
| Label | Unconjugated |
| Synonyms | MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155; SF3B1 |
| Accession No. | O75533 |
| UniProt ID | O75533 |
| Immunogen | Recombinant protein (or fragment). Please contact BioCat for more information. |
| Background | This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | Lot specific. Please inquire or refer to the datasheet included in the product pouch. |
| Buffer | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Additional Information | Conjugation service and the corresponding secondary antibody are available. |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A76658-100-EP
Name
SF3B1 Polyclonal Antibody
Price(100 ul)
Pack Size
100 ul