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SKU: A53417-050-EP

RPA3 Polyclonal Antibody

Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application ELISA, WB
Label Unconjugated
Synonyms Replication factor A protein 3, RPA3, REPA3, RPA14
UniProt ID P35244
Immunogen Recombinant Human Replication protein A 14 kDa subunit protein (1-119AA)
Background Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref. 7 Ref. 9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Primary / Secondary Primary Antibody
Isotype IgG
Buffer 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4
Clonality Polyclonal
Host Rabbit
Catalog Number
A53417-050-EP
Name
RPA3 Polyclonal Antibody
Price(50 ul)
Pack Size
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