SKU: A66442-020-EP
RFK Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA, IHC, IF |
| Label | Unconjugated |
| Synonyms | Riboflavin kinase, ATP:riboflavin 5'-phosphotransferase, Flavokinase, RFK |
| UniProt ID | Q969G6 |
| Immunogen | Recombinant Human Riboflavin kinase protein (1-154AA) |
| Background | Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A66442-020-EP
Name
RFK Polyclonal Antibody
Price(2000 ul)
Pack Size