SKU: AN302087L-100ul-ELS
Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | WB,IHC,IF,IP |
| Label | Unconjugated |
| Synonyms | SRP,HSPB,HEL-S,HSP,HSPB1,CMT2F,HEL-S-102,HMN2B,HS.76067,HSP27,HSP28,Hsp25,SRP27,28 kDa heat shock protein,DKFZp586P1322,epididymis secretory protein Li 102,Estrogen regulated 24 kDa protein,Estrogen-regulated 24 kDa protein,Heat shock 25kDa protein 1,Heat shock 27 kDa protein,Heat shock 27kD protein 1,Heat shock 27kDa protein,Heat shock 27kDa protein 1,Heat shock 28kDa protein 1,Heat Shock Protein 27,Heat shock protein beta 1,Heat shock protein beta-1,heat shock protein family B (small) member 1,Hsp 25,HSP 27,Hsp 28,Hsp B1,Stress responsive protein 27,Stress-responsive protein 27 |
| UniProt ID | P04792 |
| Immunogen | phosphorylated human HSP27 (Ser78) peptide |
| Background | Hsp27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small HSPs, HSP27 is regulated at both the transcriptional and posttranslational levels. In response to stress, the HSP27 expression increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway. Phosphorylation of HSP27 causes a change in its tertiary structure, which shifts from large homotypic multimers to dimers and monomers. It has been shown that phosphorylation and increased concentration of HSP27 modulates actin polymerization and reorganization. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG, κ |
| Concentration | 1 mg/mL |
| Clone Name | A811 |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Clonality | Monoclonal |
| Host | Rabbit |
Catalog Number
AN302087L-100ul-ELS
Name
Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody
Price(100 ul)
Pack Size