SKU: E-AB-81528-50ul-ELS
Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | WB |
| Label | Unconjugated |
| Synonyms | AGTR1, AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, HAT1R |
| Gene ID | 185 |
| UniProt ID | P30556 |
| Immunogen | A synthetic peptide of human Angiotensin II Type 1 Receptor |
| Background | Angiotensin II (Ang II),the main effector molecule of the renin-angiotensin system,exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1,also named as AT1R),thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone,cardiovascular function,salt and water homeostasis,AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease,from the regulation of blood pressure and cardiovascular homeostasis to cancer progression . |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 300 μg/mL |
| Clone Name | R07-1I6 |
| Buffer | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein |
| Clonality | Monoclonal |
| Host | Rabbit |
Resources
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Datasheet
Catalog Number
E-AB-81528-50ul-ELS
Name
Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody
Price(5000 ul)
Pack Size