SKU: AN301433L-100ul-ELS
Recombinant alpha Actinin 4 Monoclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human,Mouse |
| Application | WB,IHC,IF |
| Label | Unconjugated |
| Synonyms | ACTN,Non-muscle alpha-actinin,ACTININ,ACTN4,ACTININ-4,FSGS,FSGS1,Non-muscle alpha-actinin 4,actinin 4,Actinin alpha 4,actinin4,ACTN 4,Alpha-actinin-4,DKFZp686K23158,F actin cross linking protein,F-actin cross-linking protein,Focal segmental glomerulosclerosis 1,FSGS 1,Non muscle alpha actinin 4 |
| UniProt ID | O43707 |
| Immunogen | Recombinant human Actinin 4 fragment |
| Background | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions. May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG, κ |
| Concentration | 1 mg/mL |
| Clone Name | A128 |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Clonality | Monoclonal |
| Host | Rabbit |
Catalog Number
AN301433L-100ul-ELS
Name
Recombinant alpha Actinin 4 Monoclonal Antibody
Price(100 ul)
Pack Size