SKU: TA503521S-OR
PVRL1 (NECTIN1) Mouse Monoclonal Antibody [Clone ID: OTI6F8]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | IF, IHC, WB |
| Label | Unconjugated |
| Synonyms | CD111; CLPED1; ED4; HIgR; HV1S; HVEC; nectin-1; OFC7; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12 |
| Gene ID | 5818 |
| Accession No. | NM_002855 |
| UniProt ID | Q15223 |
| Background | This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq]. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG1 |
| Clone Name | OTI6F8 |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
TA503521S-OR
Name
PVRL1 (NECTIN1) Mouse Monoclonal Antibody [Clone ID: OTI6F8]
Price(30 ul)
Pack Size