SKU: E-AB-F1177A-1mg-ELS
Purified Anti-Mouse CD150 Antibody[TC15-12F12.2]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | Unconjugated |
| Gene ID | 27218 |
| UniProt ID | Q9QUM4 |
| Background | CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rat IgG2a, λ |
| Concentration | ≥1 mg/mL |
| Clone Name | TC15-12F12.2 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Clonality | Monoclonal |
| Host | Rat |
Catalog Number
E-AB-F1177A-1mg-ELS
Name
Purified Anti-Mouse CD150 Antibody[TC15-12F12.2]
Price(1 mg)
Pack Size