SKU: E-AB-F1060A-100mg-ELS
Purified Anti-Human CD47 Antibody[CC2C6D4]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FCM |
| Label | Unconjugated |
| Synonyms | Leukocyte surface antigen CD47, Cd47, Integrin-associated protein, IAP, |
| Gene ID | 961 |
| UniProt ID | Q08722 |
| Background | CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG1, κ |
| Concentration | ≥1 mg/mL |
| Clone Name | CC2C6D4 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1060A-100mg-ELS
Name
Purified Anti-Human CD47 Antibody[CC2C6D4]
Price(100 mg)
Pack Size