SKU: E-AB-F1137A-100mg-ELS
Purified Anti-Human CD45 Antibody[HI30]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FCM |
| Label | Unconjugated |
| Synonyms | Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45, |
| Gene ID | 5788 |
| UniProt ID | P08575 |
| Background | CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG1, κ |
| Concentration | ≥1 mg/mL |
| Clone Name | HI30 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1137A-100mg-ELS
Name
Purified Anti-Human CD45 Antibody[HI30]
Price(100 mg)
Pack Size