SKU: E-AB-12625-120ul-ELS
PRMT5 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB |
| Label | Unconjugated |
| Synonyms | 72 kDa ICln binding protein, 72 kDa ICln-binding protein, ANM5, Histone synthetic lethal 7, S. cerevisiae, homolog of, Histone-arginine N-methyltransferase PRMT5, HMT1 hnRNP methyltransferase like 5, HOMOLOG OF, SKB1, HRMT1L5, IBP72, Jak-binding protein 1, JBP 1, JBP1, PRMT 5, PRMT5, Protein arginine methyltransferase 5, Protein arginine N methyltransferase 5, Protein arginine N methyltransferase 5 N terminally processed, Protein arginine N-methyltransferase 5, S. POMBE, S. POMBE HOMOLOG OF, SKB1, SHK1 KINASE BINDING PROTEIN 1, Shk1 kinase binding protein 1 homolog, Shk1 kinase-binding protein 1 homolog, Shk1 kinase/binding protein 1, S. pombe, homolog of, SKB 1, SKB1, SKB1 homolog, SKB1: SKB1 homolog (S. pombe), SKB1Hs |
| Accession No. | NP_001034708 |
| UniProt ID | O14744 |
| Immunogen | Synthetic peptide of human PRMT5 |
| Background | Protein arginine methyltransferase 5 has been shown to interact with WD repeat-containing protein 77, CLNS1A, Janus kinase 2, SNRPD3 and SUPT5H.Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono- and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play a role in cytokine-activated transduction pathways. Negatively regulates cyclin E1 promoter activity and cellular proliferation. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 0.3 mg/mL |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-12625-120ul-ELS
Name
PRMT5 Polyclonal Antibody
Price(120 ul)
Pack Size