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SKU: A74033-100-EP

PNPLA2 Recombinant Monoclonal Antibody [1H6]

Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application ELISA, FC
Label Unconjugated
Synonyms Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2) (Desnutrin) (IPLA2-zeta) (Pigment epithelium-derived factor) (TTS2.2) (Transport-secretion protein 2) (TTS2), PNPLA2, ATGL
UniProt ID Q96AD5
Immunogen A synthesized peptide derived from Human PNPLA2
Background Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol backbone and acts coordinately with LIPE/HLS and DGAT2 within the lipolytic cascade (By similarity). Also possesses acylglycerol transacylase and phospholipase A2 activities. Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis (By similarity). May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion (By similarity).
Primary / Secondary Primary Antibody
Isotype Rabbit IgG
Clone Name 1H6
Buffer PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium Azide, pH 7.4.
Clonality Monoclonal
Host HEK293F Cell
Catalog Number
A74033-100-EP
Name
PNPLA2 Recombinant Monoclonal Antibody [1H6]
Price(100 ul)
Pack Size
100 ul
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