SKU: E-AB-92644-120ul-ELS
PMEL Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human,Mouse,Rat |
| Application | WB,IF |
| Label | Unconjugated |
| Synonyms | D12S53E,ME20,ME20-M,ME20M,P1,P100,PMEL,PMEL17,SI,SIL,SILV,gp100 |
| Gene ID | 6490 |
| UniProt ID | P40967 |
| Immunogen | Recombinant fusion protein of human PMEL |
| Background | This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-92644-120ul-ELS
Name
PMEL Polyclonal Antibody
Price(120 ul)
Pack Size