SKU: A73819-100-EP
PKM Recombinant Monoclonal Antibody [7B2]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | ELISA, WB, IHC, IF, FC, IP |
| Label | Unconjugated |
| Synonyms | Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58), PKM, OIP3 PK2 PK3 PKM2 |
| UniProt ID | P14618 |
| Immunogen | A synthesized peptide derived from human PKM2 |
| Background | Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rabbit IgG |
| Clone Name | 7B2 |
| Buffer | PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium Azide, pH 7.4. |
| Clonality | Monoclonal |
| Host | HEK293F Cell |
Catalog Number
A73819-100-EP
Name
PKM Recombinant Monoclonal Antibody [7B2]
Price(100 ul)
Pack Size
100 ul