SKU: A73950-100-EP
Phospho-MAPT (S404) Recombinant Monoclonal Antibody [11H10]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA, IHC |
| Label | Unconjugated |
| Synonyms | Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau), MAPT, MAPTL MTBT1 TAU |
| UniProt ID | P10636 |
| Immunogen | A synthesized peptide derived from Human MAPT |
| Background | Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rabbit IgG |
| Clone Name | 11H10 |
| Buffer | PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium Azide, pH 7.4. |
| Clonality | Monoclonal |
| Host | HEK293F Cell |
Catalog Number
A73950-100-EP
Name
Phospho-MAPT (S404) Recombinant Monoclonal Antibody [11H10]
Price(100 ul)
Pack Size
100 ul