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SKU: A82975-100-EP

Phospho-LCK-Y394 Polyclonal Antibody

Specifications

Specification Details
Species Reactivity Human, Mouse
Application WB, IF/ICC, ELISA
Label Unconjugated
Synonyms LSK; YT16; IMD22; p56lck; pp58lck; Phospho-LCK-Y394
UniProt ID P06239
Immunogen Synthetic peptide. Please contact BioCat for more information.
Background This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.
Primary / Secondary Primary Antibody
Isotype IgG
Buffer Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Clonality Polyclonal
Host Rabbit
Catalog Number
A82975-100-EP
Name
Phospho-LCK-Y394 Polyclonal Antibody
Price(100 ul)
Pack Size
100 ul
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