SKU: A83260-100-EP
Phospho-CRK/CRKII-Y221 Monoclonal Antibody [5V6P9]
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse, Rat |
| Application | WB, ELISA |
| Label | Unconjugated |
| Synonyms | p38; CRKII; Phospho-CRK/CRKII-Y221 |
| UniProt ID | P46108 |
| Immunogen | Synthetic peptide. Please contact BioCat for more information. |
| Background | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clone Name | 5V6P9 |
| Buffer | Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3. |
| Clonality | Monoclonal |
| Host | Rabbit |
Catalog Number
A83260-100-EP
Name
Phospho-CRK/CRKII-Y221 Monoclonal Antibody [5V6P9]
Price(100 ul)
Pack Size
100 ul