SKU: A83217-100-EP
Phospho-B-Raf-T401 Monoclonal Antibody [5G6Q5]
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Rat |
| Application | WB, ELISA |
| Label | Unconjugated |
| Synonyms | NS7; B-raf; BRAF1; RAFB1; B-RAF1; BRAF-1; Phospho-B-Raf-T401 |
| UniProt ID | P15056 |
| Immunogen | Synthetic peptide. Please contact BioCat for more information. |
| Background | This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clone Name | 5G6Q5 |
| Buffer | Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3. |
| Clonality | Monoclonal |
| Host | Rabbit |
Catalog Number
A83217-100-EP
Name
Phospho-B-Raf-T401 Monoclonal Antibody [5G6Q5]
Price(100 ul)
Pack Size
100 ul