SKU: E-AB-F1131UJ-100ug-ELS
PerCP/Cyanine5.5 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | PerCP/Cyanine 5.5 |
| Synonyms | Programmed Death-1, PD-1 |
| Gene ID | 18566 |
| UniProt ID | Q02242 |
| Background | CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rat IgG2a, κ |
| Concentration | 0.2 mg/mL |
| Clone Name | 29F.1A12 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Rat |
Resources
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Datasheet
Catalog Number
E-AB-F1131UJ-100ug-ELS
Name
PerCP/Cyanine5.5 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Price(100 ug)
Pack Size