SKU: E-AB-F1336H-100Tests-ELS
PE/Cyanine7 Anti-Human CD62L Antibody[HI62L]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FCM |
| Label | PE/Cyanine 7 |
| Synonyms | CD62L, CD62 antigen-like family member L, L-selectin, LAM-1, LECAM1, Lnhr, Ly-22, Ly22, Lymph node homing receptor, Sell |
| Gene ID | 6402 |
| UniProt ID | P14151 |
| Background | CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG2a, κ |
| Clone Name | HI62L |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1336H-100Tests-ELS
Name
PE/Cyanine7 Anti-Human CD62L Antibody[HI62L]
Price(100 tests)
Pack Size