SKU: AN00428UG-100ug-ELS
PE/Cyanine5 Anti-Mouse CD45R (B220) Antibody[RA3-6B2]
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | PE/Cyanine 5 |
| Synonyms | CD45R,B220 |
| Gene ID | 192645788 |
| UniProt ID | Q64224 |
| Background | CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker. CD19, however, may be more appropriate for B cell specificity. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rat IgG2a, κ |
| Concentration | 0.2 mg/mL |
| Clone Name | RA3-6B2 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clonality | Monoclonal |
| Host | Rat |
Catalog Number
AN00428UG-100ug-ELS
Name
PE/Cyanine5 Anti-Mouse CD45R (B220) Antibody[RA3-6B2]
Price(100 ug)
Pack Size