SKU: AN00418UG-25ug-ELS
PE/Cyanine5 Anti-Mouse CD122 Antibody[TM-Beta 1]
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | PE/Cyanine 5 |
| Synonyms | IL-2 Receptor β chain,IL-2Rβ |
| Gene ID | 16185 |
| UniProt ID | P16297 |
| Background | CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The TM-β1 antibody does inhibit IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rat IgG2b, κ |
| Concentration | 0.2 mg/mL |
| Clone Name | TM-Beta 1 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clonality | Monoclonal |
| Host | Rat |
Catalog Number
AN00418UG-25ug-ELS
Name
PE/Cyanine5 Anti-Mouse CD122 Antibody[TM-Beta 1]
Price(25 ug)
Pack Size