SKU: E-AB-F1110G-100Tests-ELS
PE/Cyanine5 Anti-Human CD8a Antibody[OKT-8]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FCM |
| Label | PE/Cyanine 5 |
| Synonyms | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
| Gene ID | 925 |
| UniProt ID | P01732 |
| Background | CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG2a, κ |
| Concentration | 5 μL/Test |
| Clone Name | OKT-8 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1110G-100Tests-ELS
Name
PE/Cyanine5 Anti-Human CD8a Antibody[OKT-8]
Price(100 tests)
Pack Size