SKU: E-AB-F1152G-100Tests-ELS
PE/Cyanine5 Anti-Human CD127/IL-7RA Antibody[A019D5]
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FCM |
| Label | PE/Cyanine 5 |
| Synonyms | CD127, CDw127, IL-7RA, IL-7Rα, Interleukin-7 receptor subunit alpha |
| Gene ID | 3575 |
| UniProt ID | P16871 |
| Background | CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG1, κ |
| Concentration | 5 μL/Test |
| Clone Name | A019D5 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
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Datasheet
Catalog Number
E-AB-F1152G-100Tests-ELS
Name
PE/Cyanine5 Anti-Human CD127/IL-7RA Antibody[A019D5]
Price(10000 tests)
Pack Size