SKU: E-AB-F1104UD-25ug-ELS
PE Anti-Mouse CD8a Antibody[53-6.7]
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | PE |
| Synonyms | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
| Gene ID | 12525 |
| UniProt ID | P01731 |
| Background | CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
| Primary / Secondary | Primary Antibody |
| Isotype | Rat IgG2a, κ |
| Concentration | 0.2 mg/mL |
| Clone Name | 53-6.7 |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Clonality | Monoclonal |
| Host | Rat |
Resources
PDF
Datasheet
Catalog Number
E-AB-F1104UD-25ug-ELS
Name
PE Anti-Mouse CD8a Antibody[53-6.7]
Price(2500 ug)
Pack Size