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SKU: E-AB-F1163D-100Tests-ELS

PE Anti-Human CD326/EpCAM Antibody[9C4]

In Stock Blue Ice

Specifications

Specification Details
Species Reactivity Human
Application FCM
Label PE
Synonyms TROP1, Ep-CAM, EpCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1
Gene ID 4072
UniProt ID P16422
Background CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.
Primary / Secondary Primary Antibody
Isotype Mouse IgG2b, κ
Concentration 5 μL/Test
Clone Name 9C4
Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Clonality Monoclonal
Host Mouse

Resources

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Datasheet

Catalog Number
E-AB-F1163D-100Tests-ELS
Name
PE Anti-Human CD326/EpCAM Antibody[9C4]
Price(10000 tests)
Pack Size
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