SKU: E-AB-17857-20ul-ELS
PCDHGB5 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | IHC |
| Label | Unconjugated |
| Synonyms | PCDH gamma B5, PCDH-GAMMA-B5, PCDHGB 5, Protocadherin gamma B5, Protocadherin gamma subfamily B 5 |
| Accession No. | NP061748 |
| UniProt ID | Q9Y5G0 |
| Immunogen | Synthetic peptide of human PCDHGB5 |
| Background | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1.4 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-17857-20ul-ELS
Name
PCDHGB5 Polyclonal Antibody
Price(20 ul)
Pack Size