SKU: A70530-100-EP
PAX3 Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IHC, IF |
| Label | Unconjugated |
| Synonyms | PAX3; CDHS; HUP2; WS1; WS3; paired box 3 |
| UniProt ID | P23760 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 241-479 of human PAX3 (NP_852122.1) |
| Background | This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A70530-100-EP
Name
PAX3 Polyclonal Antibody
Price(10000 ul)
Pack Size
10000 ul