SKU: TA501321S-OR
PANK2 Mouse Monoclonal Antibody [Clone ID: OTI3H9]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Dog, Rat, Monkey, Mouse |
| Application | FC, IF, IHC, WB |
| Label | Unconjugated |
| Synonyms | C20orf48; HARP; HSS; NBIA1; PKAN |
| Gene ID | 80025 |
| Accession No. | NM_153638 |
| UniProt ID | Q9BZ23 |
| Background | This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq]. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG2a |
| Clone Name | OTI3H9 |
| Clonality | Monoclonal |
| Host | Mouse |
Resources
PDF
Datasheet
Catalog Number
TA501321S-OR
Name
PANK2 Mouse Monoclonal Antibody [Clone ID: OTI3H9]
Price(30 ul)
Pack Size