SKU: E-AB-60300-120ul-ELS
OGG1 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | IHC |
| Label | Unconjugated |
| Synonyms | OGG1, HMMH, HOGG1, MUTM, OGH1 |
| Gene ID | 4968 |
| UniProt ID | O15527 |
| Immunogen | Recombinant fusion protein of human OGG1 (NP_002533.1). |
| Background | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1mg/mL |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-60300-120ul-ELS
Name
OGG1 Polyclonal Antibody
Price(120 ul)
Pack Size