SKU: A55510-050-EP
Nucleoprotein Polyclonal Antibody, Biotin Conjugated
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Rabies virus |
| Application | ELISA |
| Label | Biotin |
| Synonyms | NP, Nucleocapsid protein, Protein N, N |
| UniProt ID | P15197 |
| Immunogen | Recombinant Rabies virus Nucleo protein (1-450AA) |
| Background | Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases . |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A55510-050-EP
Name
Nucleoprotein Polyclonal Antibody, Biotin Conjugated
Price(50 ul)
Pack Size