SKU: TA337471-OR
NSMCE4A Rabbit Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | IF, WB |
| Label | Unconjugated |
| Synonyms | C10orf86; NS4EA; NSE4A |
| Gene ID | 54780 |
| Accession No. | NM_017615 |
| UniProt ID | Q9NXX6 |
| Background | NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
TA337471-OR
Name
NSMCE4A Rabbit Polyclonal Antibody
Price(5000 ug)
Pack Size
5000 ug