SKU: E-AB-16491-20ul-ELS
NRG1 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | WB, IHC |
| Label | Unconjugated |
| Synonyms | Acetylcholine receptor-inducing activity, Acetylcholine receptor-inducing activity, CHICK, homolog of, ARIA, Breast cancer cell differentiation factor p45, GGF, GGF2, Glial growth factor, Heregulin, heregulin, alpha (45kD, ERBB2 p185-activator), HGL, HRG, HRG1, HRGA, MST131, NDF, Neu differentiation factor, Neuregulin 1, neuregulin 1 type IV beta 1a, neuregulin 1 type IV beta 3, Neuregulin-1, NRG 1, nrg1, NRG1-IT2, NRG1, OTTHUMP00000225398, OTTHUMP00000225419, OTTHUMP00000225420, OTTHUMP00000225421, OTTHUMP00000225422, OTTHUMP00000225477, OTTHUMP00000225545, OTTHUMP00000230603, OTTHUMP00000230605, pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, ProNRG1, Sensory and motor neuron-derived factor, SMDF |
| Accession No. | NP_039258 |
| UniProt ID | Q02297 |
| Immunogen | Synthetic peptide of human NRG1 |
| Background | The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 0.6 mg/mL |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-16491-20ul-ELS
Name
NRG1 Polyclonal Antibody
Price(20 ul)
Pack Size