SKU: E-AB-15611-60ul-ELS
NECTIN1 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Application | WB |
| Label | Unconjugated |
| Synonyms | CD111, CD111 antigen, CLPED1, ectodermal dysplasia 4 (Margarita Island type), ED4, Herpes virus entry mediator C, Herpesvirus entry mediator C, Herpesvirus Ig like receptor, Herpesvirus Ig-like receptor, HIgR, HveC, MGC142031, Nectin 1, Nectin-1, OFC7, OROFACIAL CLEFT 7, OTTHUMP00000232093, OTTHUMP00000232094, OTTHUMP00000232095, Poliovirus receptor related protein 1, poliovirus receptor-like 1, Poliovirus receptor-related protein 1, PRR, PRR1, PVRL 1, PVRL1, PVRL1, PVRR, PVRR1, SK-12 |
| Accession No. | NP_002846 |
| UniProt ID | Q15223 |
| Immunogen | Synthetic peptide of human PVRL1 |
| Background | This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 0.3 mg/mL |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-15611-60ul-ELS
Name
NECTIN1 Polyclonal Antibody
Price(60 ul)
Pack Size