SKU: A55840-100-EP
NABP1 Polyclonal Antibody, FITC Conjugated
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA |
| Label | FITC |
| Synonyms | Nucleic acid-binding protein 1, Oligonucleotide/oligosaccharide-binding fold-containing protein 2A, Sensor of single-strand DNA complex subunit B2, Sensor of ssDNA subunit B2, SOSS-B2, Single-stranded DNA-binding protein 2, hSSB2, NABP1, OBFC2A, SSB2 |
| UniProt ID | Q96AH0 |
| Immunogen | Recombinant Human SOSS complex subunit B2 protein (1-204AA) |
| Background | Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A55840-100-EP
Name
NABP1 Polyclonal Antibody, FITC Conjugated
Price(100 ul)
Pack Size