SKU: TA349175-OR
Mitofusin 1 (MFN1) Rabbit Polyclonal Antibody
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | WB |
| Label | Unconjugated |
| Synonyms | hfzo1; hfzo2 |
| Gene ID | 55690 |
| UniProt ID | Q6VY07 |
| Background | The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4). |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
TA349175-OR
Name
Mitofusin 1 (MFN1) Rabbit Polyclonal Antibody
Price(10 mg)
Pack Size
10 mg