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SKU: E-MSEL-M0117-48T-ELS

Mini Sample Mouse TRACP-5b (Tartrate Resistant Acid Phosphatase 5) ELISA Kit

Colorimetric

Specifications

Specification Details
Result Output Quantitative
Species Reactivity Mouse
Sensitivity 32.81 pg/mL
Detection Range 54.69-3500 pg/mL
Design Principle Sandwich-ELISA
Detection Method Colorimetric
Synonyms ACP5,HPAP,TRACP,TRACP5a,TRACP5b,TRACP-5b,TRAP,TrATPase,TTRRAP
Gene ID 11433
UniProt ID Q05117
Target Background Tartrate-resistant acid phosphatases (TRAPIACPS) are metallic enzymes belonging to the acid phosphatase group that catalyze the conversion of orthophosphate monomers into alcohols and orthophosphates.It is a ferriglycoprotein synthesized with a 35kd monomeric proenzyme.ACP5 is involved in bone resorption and is secreted by active osteoclasts.1 Dephosphorylation of osteopontin, a bone matrix protein, subsequently promotes osteoclast detachment and migration.In colorectal cancer, ovarian cancer, breast cancer, melanoma and other cancers,ACP5 expression is associated with tumor progression.In vitro experiments have shown that down-regulated expression of ACP5 can promote the proliferation and invasion of tumor cells in colorectal cancer cell lines.In senum, ACPS has been used as a marker for thyroid metastasis, and in addition, Acps removes the lysosomal protein as a recognition marker for mannose 6-phosphate.Tartrate-resistant acid phosphatases (TRAPIACPS) are metallic enzymes belonging to the acid phosphatase group that catalyze the conversion of orthophosphate monomers into alcohols and orthophosphates. It is a ferriglycoprotein synthesized with a 35kd monomeric proenzyme.
Assay Time 3 h 30 min

Resources

PDF

Manual

Catalog Number
E-MSEL-M0117-48T-ELS
Name
Mini Sample Mouse TRACP-5b (Tartrate Resistant Acid Phosphatase 5) ELISA Kit
Price(1 x 48 Well Plate)
Pack Size
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