SKU: E-AB-60301-120ul-ELS
MICA Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human,Mouse,Rat |
| Application | WB |
| Label | Unconjugated |
| Synonyms | MIC-A,MICA,PERB11.1 |
| Gene ID | 100507436 |
| UniProt ID | Q29983 |
| Immunogen | Recombinant fusion protein of human MICA (NP_000238.1). |
| Background | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-60301-120ul-ELS
Name
MICA Polyclonal Antibody
Price(120 ul)
Pack Size