SKU: A68307-050-EP
MCM3 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA, WB, IHC, ChIP |
| Label | Unconjugated |
| Synonyms | DNA polymerase alpha holoenzyme-associated protein P1, P1-MCM3, RLF subunit beta, p102, MCM3 |
| UniProt ID | P25205 |
| Immunogen | Recombinant Human DNA replication licensing factor MCM3 protein (1-295AA) |
| Background | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
A68307-050-EP
Name
MCM3 Polyclonal Antibody
Price(50 ul)
Pack Size